Top 10 Asian Stocks To Invest In Right Now

Asian stocks rose, with the regional benchmark index poised for the biggest gain in seven months, as the yen neared 100 to the dollar after the Bank of Japan (8301) said it will maintain stimulus and loan growth in China topped estimates.

Toyota Motor Corp., the world�� largest carmaker, added 5.8 percent even as it announced a recall for faulty airbags. Sharp Corp. (6753) jumped 7.9 percent in Tokyo as the Nikkei newspaper reported profit at the electronics manufacturer will exceed it forecasts. GS Engineering & Construction Corp. slumped 15 percent in Seoul after reporting an unexpected loss.

The MSCI Asia Pacific Index (MXAP) rose for a fourth day, gaining 1.5 percent to 137.98 as of 5:11 p.m. in Tokyo, with about two stocks increasing for each that fell. All 10 industry groups on the gauge advanced. The measure, headed for the highest closing level since August 2011, climbed the past five months on speculation Japan would unleash more stimulus and amid signs the U.S. economy is recovering.

5 Best Biotech Stocks To Invest In Right Now: Newcastle Investment Corp (NCT)

Newcastle Investment Corp. (Newcastle) is a real estate investment and finance company. Newcastle invests in, and actively manages, a portfolio of, real estate securities, loans, excess mortgage servicing rights (MSRs) and other real estate related assets. The Company segments include unlevered CDOs, which include unlevered investments in deconsolidated Newcastle CDO debt; unlevered excess MSRs; non-recourse other, which includes investments financed with other non-recourse debt; recourse, which includes investments and debt repurchases financed with recourse debt; unlevered other, which includes other unlevered investments, and corporate. In April 2011, Newcastle sold its retained interests in Newcastle CDO VII, a non-consolidated VIE of Newcastle. On May 15, 2013, the Company announced the spin-off of New Residential Investment Corp. In June 2013, Newcastle Investment Corp completed the sale of 100% of the assets in Newcastle CDO IV.

Real Estate Securities

Newcastle underwrite, acquire and manage a portfolio of credit sensitive real estate securities, including commercial mortgage backed securities (CMBS), senior unsecured real estate investment trust (REIT) debt issued by REITs, real estate related asset backed securities (ABS), including subprime securities, and Federal National Mortgage Association (FNMA)/ Federal Home Loan Mortgage Corp. (FHLMC) securities. As of December 31, 2011, the Company�� real estate securities represented 47.4% of its assets.

Real Estate Related Loans

Newcastle acquires and originates loans to real estate owners, including B-notes, mezzanine loans, corporate bank loans, and whole loans. As of December 31, 2011, the Company�� real estate related loans represented 22.3% of its assets.

Residential Mortgage Loans

Newcastle acquires residential mortgage loans, including manufactured housing loans and subprime mortgage loans. As of December 31, 2011, the Company�� residential mortgage loans rep! resented 9.1% of its assets.

Operating Real Estate

Newcastle acquires and manages direct and indirect interests in operating real estate. As of December 31, 2011, the Company�� operating real estate represented 0.9% of its assets.

Excess Mortgage Servicing Rights

Newcastle invested in excess MSRs in December 2011. As of December 31, 2011, the Company�� interests in these rights represented 1.2% of its assets.

Advisors' Opinion:

• [By Albert Alfonso]

  On April 26, Newcastle Investment Corp. (NCT) finally announced the spin-off date for shares in its wholly owned subsidiary New Residential (NRZ). The distribution is expected to be made on or about May 15, 2013. Below is a helpful timeline from the presentation related to the spin-off of New Residential:

• [By Eric Volkman]

  Newcastle Investment (NYSE: NCT  ) shareholders will find a little less money in their pockets following a reduction in the company's common stock dividend. A fresh quarterly payout of $0.17 per share will be handed out on July 31 to shareholders of record as of June 13. That amount is a nickel lower than the firm's previous distribution of $0.22 per share. The upcoming payout, however, will be the first one since Newcastle completed the divestment of onetime subsidiary New Residential Investment.

• [By Matt Koppenheffer and David Hanson]

  After an incredible run-up this year, the broader market trend was downward this week, to the tune of 1.6%, but some of the stocks out there were hit particularly hard. In this video, Motley Fool financial analysts Matt Koppenheffer and David Hanson take a look at what was behind three big dives this week:�National Bank of Greece� (NYSE: NBG  ) ,�Newcastle Investment� (NYSE: NCT  ) , and�American Capital Mortgage Investment� (NASDAQ: MTGE  ) .�

Top 10 Asian Stocks To Invest In Right Now: MOJO Organics Inc (MOJO)

MOJO Organics, Inc., incorporated on August 2, 2007, engages in product development, production, marketing and distribution of CHIQUITA TROPICALS. CHIQUITA TROPICALS are a 100% fruit juice, produced under license agreement from Chiquita Brands. The Company�� product flavors include Banana Strawberry, Mango, Passion Fruit, and Pineapple.

The Company�� juices are produced without preservatives and without added sugar. The Company produces and packages the CHIQUITA TROPICALS products through production facilities and services on a contract basis.

The Company competes with The Coca-Cola Company and PepsiCo, Inc.

Advisors' Opinion:

• [By Lisa Levin]

  Catalog & Mail Order Houses: The industry gained 1.13% by 10:15 am. The top performer in this industry was Mojo Organics (OTC: MOJO), which gained 6.6%. Mojo Organics shares have jumped 361.54% over the past 52 weeks, while the S&P 500 index has gained 16.18% in the same period.

Top 10 Asian Stocks To Invest In Right Now: Grupo Aeroportuario del Sureste, SAB de CV (ASR)

Grupo Aeroportuario del Sureste, S.A.B. de C.V. (ASUR), incorporated in April 1998, is a holding company. The Company operates, maintains and develops nine airports in the Southeast region of Mexico. ASUR is a wholly owned company of the Mexican federal government. The Company operates in five segments: Cancun Airport and Subsidiaries (Cancun), Villahermosa Airport (Villahermosa), Merida International Airport (Merida) Servicios Aeroportuarios del Sureste, S. A. de C. V. (Servicios) and others. The Company�� nine airports are located in Cancun, Cozumel, Merida, Huatulco, Oaxaca, Veracruz, Villahermosa, Tapachula and Minatitlan. As of December 31, 2011, eight Mexican and 74 international airlines, including united States-based airlines, such as American Airlines and United Air Lines, were operating directly or through code-sharing arrangements in its airports. Tthe Mayan Riviera is served primarily by Cancun International Airport. The Company�� airports served approximately 17.5 million passengers, during the year ended December 31, 2011.

In 2011, the Company�� airports served a total of approximately 17.5 million passengers, approximately 57.5% of which were international passengers. In 2011, Cancun International Airport accounted for 74.2% of its passenger traffic volume and 72.8% of its revenues from its nine airports. The Company�� Cancun International Airport is located approximately 16 kilometers (10 miles) from the city of Cancun. During 2011, approximately 13.0 million passengers traveled through Cancun International Airport, principally through the old main terminal (Terminal 2) and the new terminal (Terminal 3). Merida International Airport serves the inland city of Merida and surrounding areas in the state of Yucatan. In 2011, approximately 1.2 million passengers traveled through Merida International Airport. The airport has two perpendicular runways, one with a length of 3,200 meters (2.0 miles) and another with a length of 2,300 meters (1.4 miles). The airport has one t! erminal, with four gates.

In 2011, approximately 17,732 metric tons of cargos were transported through Merida International Airport. There were 34 businesses operating in Merida International Airport, as of December 31, 2011. Cozumel International Airport is located on the island of Cozumel in the state of Quintana Roo. The airport primarily serves foreign tourists. During 2011, approximately 441,692 passengers traveled through Cozumel International Airport. Villahermosa International Airport is located in the state of Tabasco, approximately 75 kilometers (46.9 miles) from Palenque, a Mayan archeological site. During 2011, the airport served approximately 851,264 passengers. Oaxaca International Airport serves the city of Oaxaca. The airport served approximately 401,320 passengers, in 2011. There were 17 businesses operating at Oaxaca International Airport, as of December 31, 2011.

Veracruz International Airport is located in the city of Veracruz along the Gulf of Mexico. In 2011, the airport served approximately 867,438 passengers. The airport has one commercial terminal. The airport has two perpendicular runways, one with a length of 2,400 meters (1.5 miles) and another with a length of 1,523 meters (one mile). The airport also has a general aviation building for small private aircraft with 23 positions. Huatulco International Airport serves the Huatulco resort area in the state of Oaxaca on Mexico�� Pacific coast. The airport served approximately 459,640 passengers, in 2011. The airport has one runway with a length of 2,700 meters (1.7 miles). The airport�� terminal has five remote positions. The airport has a general aviation building for small private airplanes with eight positions. There were 19 businesses operating at Huatulco International Airport, as of December 31, 2011. Tapachula International Airport serves the city of Tapachula. In 2011, the airport served approximately 161,892 passengers.

The airport has one runway with a length of 2,000 meters! (1.3 mil! es). The airport has one terminal with three remote boarding positions. The airport also has a general aviation building for small private aircraft with 24 boarding positions. There were 17 businesses operating at Tapachula International Airport, as of December 31, 2011. Minatitlan International Airport is located near the Gulf of Mexico. In 2011, the airport served approximately 108,521 passengers. The airport has one runway with a length of 2,100 meters (1.3 miles). The airport�� main terminal has four remote parking positions. The airport has a general aviation building for small private airplanes with 30 boarding positions. There were 13 businesses operating at Minatitlan International Airport, as of December 31, 2011.

Aeronautical Services

The Company�� revenues from aeronautical services are derived from passenger charges, landing charges, aircraft parking charges, charges for the use of passenger walkways and charges for the provision of airport security services. Charges for aeronautical services generally are designed to compensate an airport operator for its infrastructure investment and maintenance expense. Aeronautical revenues are principally dependent on three factors, which include passenger traffic volume, the number of air traffic movements and the weight of the aircraft. Approximately 54.6% of its total revenues were derived from aeronautical services, in 2011. ASUR collects a passenger charge for each departing passenger on an aircraft.

The Company collects various charges from carriers for the use of its facilities by their aircraft and passengers. For each aircraft�� arrival, it collects a landing charge that is based on the average of the aircraft�� maximum takeoff weight and the aircraft�� weight without fuel. The Company also collects aircraft parking charges based on the time an aircraft is at an airport�� gate or parking position. It also assesses an airport security charge, which is collected from each airline based on the nu! mber of i! ts departing passengers. The Company provides airport security services at its airports through third-party contractors. ASUR also provide firefighting and rescue services at ASUR's airports.

Non-aeronautical Services

ASUR�� from non-aeronautical services are derived from commercial activities, such as the leasing of space in its airports to retailers, restaurants, airlines and other commercial tenants, and access fees charged to providers of complementary services in its airports, such as catering, handling and ground transport. In 2011, the Company opened nine commercial spaces, including six in Cancun, one in Cozumel, one in Minatitlan and one in Tapachula. Within the Company�� nine airports, it leased approximately 221 commercial premises, as of December 31, 2011, including restaurants, banks, retail outlets, currency exchange bureaus and car rental agencies. At each of its airports, ASUR earns revenues from charging access fees to various third-party providers of services, including luggage check-in, sorting and handling, aircraft servicing at ASUR's gates, aircraft cleaning, cargo handling, aircraft catering services and assistance with passenger boarding and deplaning. Seven different contractors provide handling services at its nine airports. Each of the Company�� airports has public car parking facilities consists of open-air parking lots. At each of its airports, security services are provided by independent security companies that the Company hires.

Advisors' Opinion:

• [By Seth Jayson]

  Calling all cash flows
  When you are trying to buy the market's best stocks, it's worth checking up on your companies' free cash flow once a quarter or so, to see whether it bears any relationship to the net income in the headlines. That's what we do with this series. Today, we're checking in on Grupo Aeroportuario del Sureste (NYSE: ASR  ) , whose recent revenue and earnings are plotted below.

• [By Aubrey Pringle]

  Detour Gold Corp. and Alacer Gold (ASR) Corp. each added at least 6.8 percent to pace advances among producers of raw materials. Maple Leaf Foods Inc. jumped 10 percent as the company said it might sell its 90 percent stake in Canada Bread Co. Athabasca Oil Co. slid 2.9 percent to the lowest since May to pace declines among energy producers.

Top 10 Asian Stocks To Invest In Right Now: McEwen Mining Inc (MUX)

McEwen Mining Inc. (McEwen Mining), formerly US Gold Corporation, is engaged in the exploration for and production of precious metals in the United States, Mexico and Argentina. McEwen Mining�� operating segments include USA and Mexico. The Company holds an interest in numerous exploration and development stage properties and projects in Nevada, Mexico and Argentina, as well as a 49% equity interest in the gold-silver San Jose Mine in Santa Cruz Province, Argentina. The Company holds interests in approximately 1,631 square miles of mineral concessions in west central Mexico. Its primary property in Mexico is the El Gallo Complex, located in Sinaloa state on the Sierra Madre Trend, a geological area of gold and silver mineralization. The Company holds interests in approximately 254 square miles in Nevada, United States. The Company�� Nevada properties, including its interests in the Gold Bar Project and Tonkin Complex, are located along the Cortez Trend, in north central Nevada. It also owns property, including the Limo Project, on the southern end of the Carlin Trend. On January 24, 2012, it acquired of Minera Andes Inc. (Minera Andes).

On January 24, 2012, the Company acquired a 49% interest in Minera Santa Cruz SA, owner of the San Jose Silver-Gold Mine in Santa Cruz, Argentina; a 100% interest in the Los Azules Copper Deposit in San Juan, Argentina, and a portfolio of exploration properties in Santa Cruz, Argentina. The San Jose Mine is operated by the majority owner of the joint venture, Hochschild Mining plc (Hochschild). The Company holds mineral rights and applications for mineral rights covering approximately 944 square miles in Argentina.

Tonkin Complex

The Tonkin Complex is divided functionally into five areas: the Mine Corridor, Tonkin North, Patty, Keystone and Tweed. The Tonkin Complex represents its holding in the State of Nevada at approximately 93 square miles (241 square kilometers). The Tonkin Complex is located on the Cortez Trend. During ! the year ended December 31, 2011, the Company drilled one hole, and 2,190 feet reverse circulation drilling. The Tonkin Complex also includes the Patty Project. On October 18, 2011, Barrick Gold U.S. Inc. (Barrick), the former holder of a majority of the project and operator, entered into a joint venture agreement with Rye Patch Gold U.S. Inc. (Rye Patch) under which Rye Patch has the right to acquire a 60% undivided interest in the Patty Project. As of December 31, 2011, it held a non-operating minority interest (12%). The Patty Project is a property (approximately 18.1 square miles) located in the northeast portion of the Tonkin Complex and consists of 544 unpatented mining claims. The 372 claims (included in the 1,478 under US Gold's Historic Tonkin Property) covering the area of the property, Tonkin North were previously owned by unaffiliated parties and held by the Company under a lease agreement. The lease expired on January 1, 2011. In July 2011, it acquired these claims. The Company held an interest of in 106 claims (included in the 156 under Cornerstone) in the Cornerstone property. On July 19, 2011, it acquired the Tonkin North and Cornerstone claims.

Gold Bar Complex

The Gold Bar Complex is located south of the Tonkin Complex on the continuation of the Cortez Trend. In November 2011, the Company announced the completion of a Preliminary Feasibility Study (PFS) by SRK Consulting for the Gold Bar Project. Exploration drilling at the Gold Bar Complex in 2011 totaled approximately 7,245 feet (2,208 meters) in 41 reverse circulation drill holes that were focused on extensions to the Gold Pick-Gold Ridge and Cabin Creek mineralization, as well as targets found by geologic mapping and sampling.

The Gold Pick-Gold Ridge area occurs on the Battle Mountain-Eureka mineral belt in a window of lower-plate carbonate rocks surrounded by upper-plate rocks. The lower-plate carbonates at Gold Pick-Gold Ridge consist of an east-dipping section of Silurian Lone Mountain Do! lomite, D! evonian McColley Canyon Formation, Devonian Denay Formation, and Devonian Devils Gate Limestone. Northwest-trending and northeast-trending structures cut the area; the Gold Pick mineralization is localized in an apparent northwest-trending horst of McColley Canyon Formation, which is cut by a series of northeast-trending structures.

Limo Property

The Limo Property is located in east-central Nevada. The Limo Property position totals approximately 44.5 square miles (115 square kilometers). Gold mineralization has been identified in numerous places along the 15 mile (24 kilometers) length of the property. Exploration drilling at the Limo Property in 2011 totaled approximately 59,157 ft. (18,031 meters) in 10 diamond drill core holes and 70 reverse circulation drill holes. The drilling was focused on two targets, Cadillac and Continental, outside the existing mineralization. The mineral interests controlled by the Company at the Limo property consist of 1,392 contiguous claims that cover approximately 44.5 square miles (115 square kilometers), plus 15 claims (for a total of 1,407) near the southern boundary of the property that were acquired through a lease in August 2011. Its land package extends for about 15 miles (24 kilometers), and covers the western side of the southern Cherry Creek Range.

Battle Mountain Complex

The Battle Mountain Complex is located within Humboldt and Lander Counties in the valleys and on the flanks of the mountains surrounding Battle Mountain on the Cortez Trend north of our Tonkin complex. Battle Mountain, Nevada. In 2011, exploration drilling in the Battle Mountain Complex totaled 2,205 feet (672 meters). Work during 2011, also included geologic mapping, soil and rock sampling. Results of this work identified two target areas, Medea and Lucky Strike, on its BMX property. Three holes were drilled on the Medea prospect during 2011.

Other United States Properties

The Company acquired additional mineral! properti! es in Nevada. The mineral properties included in the acquisition of Tone (Roberts Creek, Kobeh, Gold Bar North, South Keystone, Big Antelope Springs, Red Ridge, Fish Creek and Kent Springs) are generally subject to a 1% net smelter return royalty interest in favor of KM Exploration Ltd. Certain properties (Roberts Creek, Kobeh, Gold Bar North, South Keystone and Big Antelope Springs) are also subject to earn-in rights in favor of Teck Cominco American Incorporated (Teck).

Alaska

On July 1, 2011, its Company and Select Resources Corporation, Inc. (Select) signed a four-year Exploration Lease and Purchase Option Definitive Agreement (the Definitive Agreement) with respect to the Richardson Mineral Project (Richardson) in the Tintina Gold Belt of Alaska. Under the terms of the Definitive Agreement, it acquired an exploration lease for the Richardson project, and an exclusive option to purchase a 60% interest in the project and enter into a joint venture with Select. The Richardson project is located 70 miles (115 kilometers) southeast of Fairbanks, Alaska, and covers an area of approximately 52 square miles (136 square kilometers). Extensive field sampling and mapping, airborne geophysics, and three core holes were completed in 2011. Drilling at the Richardson Project in Alaska during 2011, included three holes and 2, 863 feet core drilling.

Mexican Properties

The Company has a property in Mexico, called the El Gallo Complex, which includes the El Gallo, Magistral, and Palmarito deposits in Sinaloa state. The Company control mineral concessions of approximately 1,631 square miles (4,224 square kilometers) located in the Mexican states of Sinaloa and Nayarit. It holds its interests through ownership of Pangea Resources Inc., which in turn holds 100% ownership of Compania Minera Pangea S.A. de C.V. (Minera Pangea). The El Gallo Complex is located in Sinaloa state, northwestern Mexico in Mocorito Municipality. The El Gallo Complex is being developed in tw! o phases.! The El Gallo Project lies within two of its controlled concessions, Rocio Fraccion A and Pangea. These concessions have an area of 86,764 acres and 3,946 acres respectively. It controls the properties immediately surrounding El Gallo. Exploration work completed in 2011 at El Gallo consisted of core and conventional rotary drilling. The mineralization at the Magistral Mine Property is classified as a low-sulfidation epithermal gold-silver mineral system. During 2011, 203 core holes were drilled for a total of 88,891 feet (26,088 meters).

Other Exploration Areas

During 2011, it drill-tested a number of prospective exploration targets throughout the El Gallo district, which resulted in the discovery of four new veins. Three veins, Los Mautos, Mina Grande, and Haciendita were all located six miles (10 kilometers) north of El Gallo, and the fourth vein, San Dimas, is located 6 miles (10 kilometers) south of El Gallo.

Advisors' Opinion:

• [By Travis Hoium]

  What: Shares of McEwen Mining (NYSE: MUX  ) jumped as much as 12% today after the company released production figures.

  So what: In the second quarter, the company produced 35,955 gold equivalent ounces, 30% higher than a year earlier. Both of the company's mines are producing at solid levels, and management thinks it can reach 130,000 gold equivalent ounces this year.�

• [By Luke Jacobi]

  McEwen Mining (NYSE: MUX) closed down, falling 5.14 percent to $2.40 following a Seeking Alpha article commenting on news of an Argentinian taxation raid on mining companies.

• [By Jake L'Ecuyer]

  McEwen Mining (NYSE: MUX) was also down, falling 4.35 percent to $2.42 following a Seeking Alpha article commenting on news of an Argentinian taxation raid on mining companies Johnson Controls (NYSE: JCI) was down, falling 2.31 percent to $41.55.

Top 10 Asian Stocks To Invest In Right Now: Prumo Logistica SA (LLXL3)

Prumo Logistica SA, formerly LLX Logistica SA (LLX), is a Brazil-based company primarily engaged in the sector of port logistic services. The Company builds and develops the Acu Port, located in Sao Joao da Barra, in the north of the State of Rio de Janeiro. The Industrial Complex Acu Port has two port terminals (T1 and T2) and the capacity to handle various types of cargo, such as petroleum, iron ore, coal, solid and liquid bulk and general cargo. The Company�� subsidiaries include LLX Minas-Rio Logistica Comercial Exportadora SA, LLX Acu Operacoes Portuarias SA and LLX Brasil Operacoes Portuarias SA. In October, 2013, EIG LLX Holdings SARL reached a 52.82% stake in the ordinary share capital of the Company. Advisors' Opinion:

• [By Denyse Godoy]

  A committee of exchange executives, banks and brokerages developed the changes to the benchmark index. BM&FBovespa said on its website that it hadn�� made changes to the gauge�� methodology since its inception in 1968. LLX Logistica SA (LLXL3), the shipping unit that Batista founded, is the second-lowest priced stock on the Ibovespa after dropping 36 percent this year to 1.53 reais.

Top 10 Asian Stocks To Invest In Right Now: RenaissanceRe Holdings Ltd.(RNR)

RenaissanceRe Holdings Ltd., together with its subsidiaries, provides reinsurance and insurance products in the United States and internationally. The company offers property catastrophe reinsurance products, including catastrophe excess of loss reinsurance, excess of loss retrocessional reinsurance, and insurance-linked securities; and specialty reinsurance products, such as catastrophe exposed workers? compensation, surety, terrorism, energy, aviation, crop, political risk, trade credit, financial, mortgage guarantee, catastrophe-exposed personal lines property, casualty clash, other casualty lines, and other specialty lines of reinsurance. It also provides various insurance products consisting of commercial property, including catastrophe-exposed commercial property products; commercial multi-line comprising commercial property and liability coverage, such as general liability, automobile liability and physical damage, building and contents, and professional liability; and personal lines property, including homeowners personal lines property coverage and catastrophe exposed personal lines property coverage. The company offers its products and services primarily through intermediaries. RenaissanceRe Holdings Ltd. was founded in 1993 and is headquartered in Pembroke, Bermuda.

Advisors' Opinion:

• [By David Sterman]

  Lastly, conservative investors may want to check out Renaissance Reinsurance (NYSE: RNR) which has been buying back shares for seven straight years, reducing the share count by 30% in that time. The newly announced buyback plan, which could absorb up to 13% of the additional share count, is a primary focus now. But when share buybacks are no longer the focus, then robust dividend growth will likely be the norm as this company can afford to support a $4.50 a share dividend (equating to a 5% yield) while still keeping the payout ratio below 50%.

Top 10 Asian Stocks To Invest In Right Now: Epizyme Inc (EPZM)

Epizyme, Inc., incorporated on November 1, 2007, is a clinical stage biopharmaceutical company that discovers, develops and plans to commercialize personalized therapeutics for patients with genetically defined cancers. The Company systematically identify the genetic alterations that create cancer causing genes, called oncogenes, select patients in whom the identified genetic alteration is found and then design small molecule therapeutics to inhibit the oncogene. The clinical development plan for each of its product candidates is directed towards patients with a particular genetically defined cancer.The Company is conducting a Phase I clinical trial of its advanced product candidate, EPZ-5676, an inhibitor targeting the DOT1L HMT, for the treatment of mixed lineage leukemia (MLL-r). The Company has identified its two lead product candidates using its product platform.

EPZ-5676-DOT1L Inhibitor

EPZ-5676 is an intravenously administered small molecule inhibitor of DOT1L. The Company is developing EPZ-5676 for the treatment of MLL-r, an aggressive subtype of the two most common forms of acute leukemia, ALL and AML. Patients with MLL-r are routinely diagnosed with existing technologies that are commonly used in clinical setting. The Company�� Phase 1 clinical trial of EPZ-5676 is an open label, multicenter trial that has two phases.

EPZ-6438-EZH2 Inhibitor

The Company is developing EPZ-6438 as an orally available small molecule inhibitor of EZH2 for the treatment of non-Hodgkin lymphoma patients who have an oncogenic point mutation in EZH2. EZH2 is an HMT that can become oncogenic and cause non-Hodgkin lymphoma and a range of other solid tumors. Two types of non-Hodgkin lymphoma, diffuse large B-cell lymphoma of germinal-center origin, or DLBCL, and follicular lymphoma, or FL, are particularly associated with an EZH2 point mutation. There are no therapies approved specifically for the treatment of cancer associated with an EZH2 point mutation.

Advisors' Opinion:

• [By John Udovich]
  Follow-on Stock Offerings From Small Cap Biotech Stocks. Thanks to the boom in biotech IPOs along with the sector�� overall performance, already listed biotechs have the option to ask investors for more cash in the form of a follow-on offering. Recently, FierceBiotech.com noted how four small cap biotechs raised $276 million from follow-on offerings in just one day last week. These small caps�included Epizyme Inc (NASDAQ: EPZM) which raised $88 million, Halozyme Therapeutics, Inc (NASDAQ: HALO) which raised $100 million, Agenus Inc (NASDAQ: AGEN) which raised $52 million and Idera Pharmaceuticals Inc (NASDAQ: IDRA) which raised $36 million. FierceBiotech.com noted that the�steady flow of about $4.5 billion a year in venture cash�along with�more than $3.5 billion from IPOs last year plus all of the�follow-ons are helping to foster both company growth and�accelerate drug�development programs. Mixed Bag for Biotech IPOs. Last Wednesday also saw two small cap biotech IPOs fizzle in one day�with small cap T cell vaccine developer�Genocea Biosciences Inc (NASDAQ: GNCA) raising $60 million but then ending the day down 8.3% to close at $11 while Dutch drug developer uniQure NV (QURE) raised $81.9 million but fell more than 14% to $14.61. However, orphan drug stock Auspex Pharmaceuticals Inc (NASDAQ: ASPX), which is developing�drugs to treat orphan diseases like Tourette syndrome, saw a 30.5% gain to close at $15.66 and raise $84 million. The Boston Globe quoted Michael Ringel, a partner and managing director at Boston Consulting Group who focuses on health care business, as saying:

  ��he mood is incredibly positive. Capital is flowing. [The biotech IPOs]��have been burning hot. I think it�� too early to suggest that is changing. I can�� predict the overall economy any better than anyone else, but I would expect a pretty good year for IPOs.��/p>